ABSTRACT

Introduction .................................................................................................................................... 910 Global Dissemination of Parasites ............................................................................................ 910

Adaptations for Parasitism as a Way of Life .................................................................................. 910 Parasite Life Cycles: Denitions ............................................................................................... 910 Mechanisms of Pathogenesis .................................................................................................... 911

Host Factors ................................................................................................................................... 911 Immune Response ..................................................................................................................... 911

Humoral Pathway ................................................................................................................. 911 Cell-Mediated Immunity ...................................................................................................... 915

Parasite Evasion of the Immune Response ............................................................................... 915 Human Parasitic Diseases .............................................................................................................. 915

Protists ....................................................................................................................................... 917 Malaria.................................................................................................................................. 917 Plasmodium vivax ................................................................................................................ 917 African Sleeping Sickness .................................................................................................... 918 American Trypanosomiasis .................................................................................................. 918 Babesiosis ............................................................................................................................. 918 Cryptosporidiosis and Cyclosporiasis .................................................................................. 919 Toxoplasmosis ......................................................................................................................920 Leishmaniasis .......................................................................................................................920 Giardiasis and Amebiasis .....................................................................................................920