ABSTRACT

The versatility of the model becomes useful when trying to model a specifi c pathology such as, for example, infection by a complex virus, allergies or cancer. The modus operandi is always the same. First, identify the key players as agents, and then translate immunological knowledge about their behaviour into logical rules. Finally, after having dealt with all the technicalities of the implementation, validate the model by comparing the outcome with experimental data, keeping in mind that some simplifi cations and approximations are needed even when interpreting the model output.