chapter  8
Difficult-to-treat patient groups
Pages 10

Patients with cirrhosis induced by chronic hepatitis C do respond to therapy, albeit at

a lower rate than patients with lesser degrees of fibrosis. Follow-up studies comparing treated and untreated patients suggest that the rate of development of decompensated disease and the development of liver cell cancer is reduced in patients who have received interferon therapy. This benefit is most marked in patients who have cleared the virus, but even patients who have not responded to therapy by eliminating the virus may have a reduced rate of complications.