ABSTRACT
Habitual abortion is usually defined as at least three consecutive fetal losses. It affects 0.3% of the pregnant population in proportion to a 75% live birth rate after three consecutive fetal losses.1,2 Recurrent fetal loss often has a broader definition of at least three first trimester fetal losses and/or ≥two second trimester fetal losses. It affects between 1% and 2% of the pregnant population. Factors that are major determinants of the risk of miscarriage are; increasing maternal age, the number of prior fetal losses, and if cardiac activity had been detected or not.2 The pathogenesis of recurrent fetal loss in the majority of cases is still unclear. Several causes have been suggested: chromosome aberrations, thrombophilias, thyroid abnormality, microparticles, and complement activation.3
