ABSTRACT
The investigation and treatment of women with recurrent miscarriage (RM) has historically been based on anecdotal evidence, personal bias of physicians, and the results of small uncontrolled studies.1 This has led to the situation where women have been subjected to treatments of no proven benefit, some of which have subsequently been demonstrated to be harmful.2 This is unacceptable. Indeed, in the current climate in which patient demands and expectations for a “treatment/cure” of their reproductive failure is ever increasing, it is incumbent upon clinicians to reject previous practice and embrace an evidencebased approach to the management of RM.
