ABSTRACT
In the 1950s laboratory tests began to be used as diagnosis tools, which led to spectacular increase in demand for them. The huge number of analyses required and the need to have results in a short time could only be met by the advent of automatic analytical methods such as ow methods. Flow techniques arose in 1957 with segmented ow analysis (SFA) [1], which afforded not only substantially increased throughput but also substantial savings in samples and reagents. SFA laid the foundations for modern ow techniques. Since then ow techniques have been in continuous evolution toward new developments in the search of low-cost highly reproducible fast determinations.
