ABSTRACT
Diffuse large B-cell lymphoma is the most frequent lymphoma type in the liver. It represents the primary or secondary lymphoma and forms large masses often with necrotic and cystic changes. Lymphomatous infiltrate usually involves portal triads with later expansion into liver parenchyma. Lymphoepithelial lesions in the bile ducts are often present. Lymphomatous cells are small to medium in size, often with a monocytoid appearance. Burkitt Lymphoma is a high-grade lymphoma, which involves the lymph node and/or extranodal sites, but liver involvement is rare and most often represents systemic disease. Lymphomatous cells are medium in size and monotonous in appearance with mitotic figures and histiocytes, creating a “starry-sky” pattern. Peripheral T-cell lymphoproliferative disorders have to distinguish from T-cell-rich infiltrates in the liver, including inflammatory processes and reactive T cells accompanying B-cell lymphomas or Hodgkin lymphoma (HL). Classical HL usually presents with superficial adenopathy.
