ABSTRACT
Primary lymphomas of the lung are rare and majority of them are represented by marginal zone lymphoma followed by diffuse large B-cell lymphoma, and sporadic cases of Hodgkin lymphoma (HL), mantle cell lymphoma, follicular lymphoma, B-cell chronic lymphocytic leukemia, anaplastic large cell lymphoma, and peripheral T-cell lymphoma. The lymphoid infiltrate shows predominance of small- to occasionally medium-sized lymphocytes and scattered larger cells with centroblastic morphology. The lymphoid cells often display a typical monocytoid appearance. Plasma cells are present at various proportions and are often monotypic. Reactive germinal centers are usually present and show features of colonization by neoplastic lymphocytes. The localized form of amyloidosis has been associated with immunoglobulin light chains and with low-grade lymphoma. Classical HL frequently involves mediastinum, and may extend into lung parenchyma and it usually affects younger patients. Mediastinum is one of the most common location for classical HL.
