ABSTRACT
The overall survival rate after childhood cancer has improved signicantly over the past decades, and thus more and more adults will be childhood cancer survivors. Subsequently, this particular group of patients will be found more frequently in fertility clinics seeking help to have a child, now and in the future. It is important to understand that women who have been treated in childhood for a cancer may present with various physical problems that can be attributed to the chemo-or radiation therapy they received as a child, and that may pose a challenge to obtaining and completing a pregnancy and delivery. Both chemotherapy and mediastinal radiation are known to cause long-term cardiac and pulmonary morbidity.1 Cardiomyopathy and arrhythmias are well-known, albeit rare, sequelae to chemotherapy, and mediastinal radiation may cause pericardial damage. Pulmonary brosis is a known sequela to both radiation and chemotherapy, and all of these conditions may pose a challenge to the woman in pregnancy, where a growing foetus already makes signicant demands on the mother’s cardiac and pulmonary function.
