ABSTRACT

Curious Facts ............................................................................... 308 Curious Facts ............................................................................... 309 Curious Facts ............................................................................... 313

APPENDIX-B ....................................................................................... 350

Appendix-C ........................................................................................... 353 Appendix-D ........................................................................................... 369 Keywords .............................................................................................. 380 References ............................................................................................. 381

10.1 INTRODUCTION

Over the recent decades, the fabrication of biodegradable nanofibers for many biomedical applications, such as tissue engineering, drug delivery, wound dressing, enzyme immobilization, and so on, has been recorded. Nanofiber fabrics have unique characteristics, such as very large surface area, ease of functionalization for various purposes and superior mechanical properties. Electrospinning (Figure 10.1) is an important technique that can be used for the production of polymer nanofibers with diameters from several micrometers down to tens of nanometers. In electrospinning, the charged jets of a polymer solution, collected on a target, are created by using an electrostatic force. Many parameters can influence the quality of fibers, including the solution properties (polymer concentration, solvent volatility and solution conductivity), the governing variables (flow rate, voltage and tip-to-collector distance), and the ambient parameters (humidity, solution temperature, air velocity in the electrospinning chamber) [1-12].