ABSTRACT

Plasma-based ambient ionization mass spectrometry techniques, such as DART (direct analysis in real time), FAPA (owing atmospheric pressure afterglow), DBDI (dielectric barrier discharge ionization), ASAP (atmospheric solids analysis probe), DAPCI (desorption atmospheric pressure chemical ionization), and some others, are gaining growing interest as they do not require time-consuming sample preparation, are rapid, and work under ambient experimental conditions. An additional advantage is also a possibility for samples analysis in gas, liquid, or solid forms. These techniques can be applied in a wide range of applications, such as warfare agents’ detection, chemical reactions control, mass spectrometry imaging, identication of polymers, food safety monitoring, drug and pharmaceutical analysis, medical diagnostics, forensic research, biochemical analyses, etc.