ABSTRACT

Epidermal nevus is a term that encompasses hamartomatous proliferations of epithelium that originate from embryonal ectoderm. They are classified on the basis of the main histologic component: keratinocytes, sebaceous gland, pilosebaceous unit, eccrine gland, or apocrine gland. Clear cell acanthoma is a benign epidermal neoplasm composed of keratinocytes with ample pale cytoplasm and centrally placed nuclei. It consists of a well-demarcated, solitary, shiny, and brown to orange papule or nodule. Inverted Follicular Keratosis is an uncommon benign tumor of the follicular infundibulum that can be confused, both clinically and histologically, with several benign and malignant skin conditions. Seborrheic keratoses are the most common benign skin tumor in older individuals characterized by well-demarcated papules with a verrucous surface. Warty dyskeratoma is a benign papulonodular lesion characterized by an endophytic proliferation of squamous epithelium, typically occurring in relation to a folliculosebaceous unit and showing prominent areas of acantholysis.