ABSTRACT

The secondary open-angle glaucomas comprise a number of conditions in which intraocular pressure becomes elevated through a variety of mechanisms other than primary dysfunction of the trabecular meshwork. Pigmentary glaucoma is a secondary open-angle glaucoma in which released iris pigment interferes with trabecular meshwork function, leading to elevated intraocular pressure. Exfoliation syndrome is a common cause of secondary open-angle glaucoma in many populations. The use of corticosteroids in any form may lead to the development of secondary open-angle glaucoma. Nonpenetrating injuries of the eye secondary to blunt trauma are usually related to the anterior-to-posterior compression of the eye with secondary equatorial stretching. Increased intraocular pressure secondary to steroid therapy or to increased aqueous production with resolving inflammation may confuse the clinical picture. Glaucoma is found more frequently in metastases to the iris and ciliary body than in metastases to the choroid.