ABSTRACT
Antioxidants scavenge and prevent the formation of free radicals, so they are exceedingly important for the treatment and management of these kinds of diseases (Emerit et al. 2004). Therefore, in recent years, there has been an increasing interest in nding new antioxidant compounds. The damages caused by oxidative stress occur due to the imbalance between prooxidants and antioxidants. Then antioxidant barrier represented mainly by enzymes and nonenzymatic antioxidant factors are weakened, which allows the accumulation of cytotoxic compounds that consume antioxidant reserves of the body (Sies 1997; Padurariu et al. 2013). Reactive oxygen species (ROS) can react with all biological macromolecules and cells. The rst reaction produces a new radical, and this one can create a chain reaction. Polyunsaturated fatty acids (PUFAs) are the best targets since they have multiple double bonds. Removal of a hydrogen atom from a PUFA initiates the process of lipid peroxidation (Suzen 2013).
