ABSTRACT
Despite the capabilities of MLC, the technique has not however received enough attention in solving the "real world" problems in analytical laboratories, for two apparent reasons. First, RPLC with aqueous-organic eluents is a powerful and popular technique that would be very difficult for any other chromatographic method to replace. A reasonable argument is needed for an alternative technique. Second, the two techniques (MLC and conventional RPLC) have been often compared in an area in which MLC has clear disadvantages, that is, for the separation of uncharged and hydrophobic compounds. MLC is a poor choice in this respect from the three important aspects of efficiency, elution strength and selectivity.
