ABSTRACT

Base: MW 444; hydrochloride: MW 481; pKa 3.3, 7.7 (acidic), 9.7 (basic). 1 g of the hydrochloride dissolves in 10 ml of water. Store in airtight containers. The drug should be protected from light.

Doxycycline

Base: Monohydrate MW 462; pKa 3.5, 7.7 (acidic), 9.5 (basic). Slightly soluble in water. Store in air-tight containers. The drug should be protected from light.