ABSTRACT

Erythrocytes, leukocytes and platelets are all derived from bone marrow, although each cell subtype is derived from bone marrow at different sites of the body; certain types of leukocyte are also derived from lymphoid tissues such as the thymus gland. Any dis­ ruption of bone marrow activity, for example following administration of cytotoxic drugs, has the effect of interfering with blood cell formation and therefore has a profound effect on the function of the whole body. Disorders of blood cell formation and the drugs used for their treatment are discussed below.