ABSTRACT

In the course of the development of capillary electrophoresis [9,10], the idea of electroosmotic pumping of mobile phase through a packed bed was taken up again. In their landmark paper in 1981, Jorgenson and Lukacs [11] showed for the first time the possibility of performing reversed-phase chromatography in packed capillaries employing virtually the same apparatus as developed for CE. Since these pioneering works, development of CEC has started and several names have been coined for this type of capillary separation technique: liquid chromatography with electroosmotic flow [12], electroendosmotically driven liquid chromatography [13], electrically driven liquid chromatography [14], electroendosmotic capillary chromatography [15], electrokinetic chromatography with packed capillaries [16], and capillary electrochromatography [17,18].