ABSTRACT
Bacterial poly(3-hydroxybutyrate) (PHB) as member of natural polymer family of polyalcanoates has been widely used in the innovative biomedical areas owing to relevant combination of biocompatibility, transport characteristics and biodegradation without toxic products formation. The review presents a comprehensive description of hydrolysis and enzymatic degradation during long-time period preferably under laboratory condition (in-vitro) and as medical implants (in-vivo). Besides, the focus of review is devoted to the literature comparison of different works in PHB degradation and its biomedical application including work of authors.
