ABSTRACT

STATs are emerging as a significant family of oncogenes in a large number of human tumors including both tumors of the blood and solid tumors including lung, prostate and head and neck cancers.2 Constitutively active STATs were first described in breast carcinoma.3 In order to fully understand the role of STATs in the diseased breast, it is first necessary to evaluate the physiologi­ cal role of this transcription factor family in the healthy mammary gland.