Chromosome Behavior in Differentiation
The influence of chromosome on the regulation and control of differentiation of organs, is an expression of its dynamic behavior. Of the components that enter into composition of chromosomes, in several organisms, lysine rich histones are often replaced by arginine rich histones. B. McClintock too claimed that transposon or mobile sequences in chromosomes often play an important role in programmed cell differentiation. In chromosomal control in differentiation, both structural and behavioral characteristics of chromosomes are involved. A large number of species, both plants and animals, undergo endomitotic replication during differentiation. The transcribing capacity of different genes, and as such chromosome segments, is also under genetic control. P. R. Cook noted that cellular differentiation is controlled by the development of the higher order of polymorphism of chromosomes. Variability of the DNA content from organ to organ has been recorded in various species.