ABSTRACT

Classification Scheme RER rough endoplasmic reticulum RF rheumatoid factor rHuIFNγ recombinant human IFNγ (or other cytokine) rHuTSH recombinant human TSH RNA ribonucleic acid RNP ribonucleoprotein RT-PCR reverse transcriptase-polymerase chain reaction SAA serum amyloid-associated protein SAARD slow-acting antirheumatic drug SALT skin-associated lymphoid tissue SARs suspect adverse reactions SARSS suspect adverse reaction surveillance scheme s/c subcutaneous SCID severe combined immunodeficiency SI stimulation index SIBO small intestinal bacterial overgrowth

SLE systemic lupus erythematosus SmIg surface membrane immunoglobulin (SmIg+,

SmIgM, SmIgD) SNP single nucleotide polymorphism SPC summary of product characteristics SPE serum protein electrophoresis SRID single radial immunodiffusion SRMA steroid responsive meningitis-arteritis STAT signal transducers and activators of transcription Tc T cytotoxic (cell) TCR T cell receptor TEN toxic epidermal necrolysis TGF transforming growth factor Th T helper (cell) TK1 thymidine kinase 1 TLI trypsin-like immunoreactivity TNF tumour necrosis factor TPMP thiopurine methyltransferase Treg T regulatory (cell) TRH thyrotropin releasing hormone TSH thyroid stimulating hormone TUBA total unconjugated bile acids UV ultraviolet (light) VCAM vascular cell adhesion molecule VKH Vogt-Koyanagi-Harada syndrome VMD Veterinary Medicines Directorate VPC Veterinary Products Committee WBCs white blood cells X-SCID X-linked severe combined immunodeficiency

T cell

B cell

plasma cell

dendritic cell (APC)

macrophage (APC)

neutrophil

eosinophil

mast cell

natural killer cell

endothelium or capillary

immunoglobulin

T cell receptor

antigenic peptide

MHC class II

MHC class I

Fc receptor

antigen

platelets

T

B

NK