ABSTRACT

Conformal and Intensity-Modulated Radiotherapy . . . . . . . . . . . . . . . . . . . . . . . . . 943

Steve Webb

Chapter 44

Intensity-Modulated Radiotherapy: Practical Aspects . . . . . . . . . . . . . . . . . . . . . . . 975

C.-M. Charlie Ma (with Helen Mayles and Philip Mayles)

Chapter 45

Stereotactic Techniques . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 987

Jim Warrington

Chapter 46

Proton Beams in Radiotherapy . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1005

Alejandro Mazal

Chapter 47

Total Body Irradiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1033

Philip Mayles (with Ginette Marinello)

Chapter 48

Total Skin Electron Irradiation . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1043

David Thwaites and Alan McKenzie (with Ginette Marinello)

Chapter 49

High-LET Modalities . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1053

Roland Sabattier, Oliver Ja

¨

kel, and Alejandro Mazal

References . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 1069

In this Part we cover all those external-beam radiotherapy techniques that, for a variety of

reasons, do not easily fit into conventional treatment planning (Part G). Today Conformal

Therapy (CFRT)* is no longer considered to be a special technique, but it is used here as a

foundation for introducing Intensity-Modulated Radiotherapy (IMRT) which is a particular

form of CFRT (Chapter 43). The deceptively simple idea of introducing another degree of

freedom in treatment planning, namely to create deliberate variations or modulations in the

intensity across the beam, has spawned an unprecedented period of development in treatment

machine technology (e.g. dynamically controlled multileaf collimators (MLC)), in treatment

planning systems capable of so-called inverse planning, and also in the search for trulymeaningful

criteria by which to judge the merit of a treatment plan (see Part G, Chapter 36). A separate

chapter is devoted to the clinical implementation of IMRT (Chapter 44).