ABSTRACT
Fig. 2 Obesity rates, by state, for the USA in 2008. Th is illustration is made available for use by the CDC website.
Fig. 3 Fibrinolytic pathway. Blue arrows denote stimulation and red arrows denote inhibition (Source: Wikipedia, the Free Encyclopedia). Fibrinolysis is normally mediated by plasmin, which circulates in blood as its pro-enzyme, plasminogen. Conversion and activation of plasminogen into plasmin is eff ected by two plasminogen activators: tissue-type plasminogen activator (t-PA) and urokinase-type plasminogen activator (u-PA). Th e process of fi brinolysis can thus be inhibited by inhibition plasmin itself, by α-2 anti-plasmin, or by inhibition of the plasminogen activators by PAI-1.
