ABSTRACT
Chlorinated pesticides and PCBs are totally synthetic chemicals. They were first developed in the early part of the 1900s, but many ceased being used during the mid-1970s in the United States, Canada, and most developed nations due primarily to human health concerns. However, a few OCs such as endosulfan are still in use, and others are being manufactured and used in third world nations. DDT, for instance, remains the chemical of choice for mosquito control in malaria-ridden areas. Both PCBs and chlorinated pesticides are persistent, so their residues are still found in environmental matrices around the globe. Dioxins and furans are products of combustion, including
9.1 Cellular Metabolism of Organic Contaminants ................................................................... 262 9.2 Polychlorinated Biphenyls, Dioxins, and Furans .................................................................. 263
9.2.1 Amphibian Residues ................................................................................................. 263 9.2.2 Effects of PCBs, Dioxins, and Furans ......................................................................268
