ABSTRACT

The conventional NIR region lies between 700 and 2500 nm. Nearinfrared spectra arise from absorption bands resulting from overtones and combinations of fundamental mid-IR (MIR) stretching and bending modes. They have low molar absorptivity with broad, overlapping peaks. The low absorptivity is a primary reason for the usefulness of the method for analysis of intact dosage forms. These absorbance arise from C-H, O-H, and N-H bonds.