ABSTRACT
It is universally recognized that stress can have an impact on the erythroid (and also leukocytic) values of the circulating blood. This is part of the alarm reaction that was rst recognized by Selye (1936) and Harlow and Selye (1937). Investigators dealing with nonhuman primates are typically knowledgeable about the occurrence of modication of the blood picture due to stress and are also interested in its quantitative and durational aspects. In many cases, the alarm reaction (synonym: stress reaction) is the result of relatively straightforward occurrences of experimental studies such as the use of restraint or a squeeze-back cage, placement in a primaterestraint chair, the change from a social existence to a solitary caged life, or vice versa, relocation from one laboratory to another, the initiation of experimental studies on an individual monkey that has been and continues to live within its own cage (e.g., phlebotomies, intubations, injections), or temporary transfer from the home cage to a platform for a procedure followed by a return to the home cage.
