ABSTRACT

In this final chapter, we consider the future of Mendelian randomization within the wider context of genetic epidemiology. We divide the chapter into two sections. First, we discuss methodological developments in instrumental variable techniques which enable more sophisticated Mendelian randomization analyses. Secondly, we discuss applied developments, such as advances in genotyping and other high-throughput cell biology techniques, which widen the scope for future Mendelian randomization analyses.