chapter  32
16 Pages

Botanicals in Sun Care Products

Introduction 657

Botanicals of Specific Interest 659

Botanically Derived Sunscreens and SPF Boosters 659

Botanicals as Photochemoprotective Agents 660

Botanicals in Sun Care Products 661

Quality Control: Methods of Analysis 661

Recent Research Techniques: Biological Assays and

Cell Culture 665

Biological Assays of Interest for Screening Botanicals in

Sun Care Products 666

Conclusion 669

References 669

INTRODUCTION

Sun exposure has long been considered a healthy benefit of outdoor activity.

Exposure to ultraviolet radiation (UVR) can stimulate vitamin D synthesis in

the body and may promote immune tolerance toward certain antigens such as

myelin autoantigens (1). Conversely, epidemiological data confirmed by research

of the last 20 years have shown that exposure to UVR is a major risk factor for

various skin cancers, premature aging of the skin commonly referred to as

photoaging, and alteration of the skin’s immune functions (2). More recently,

research has shown that although sunlight and oxygen are essential for life,

exposure to UVR and infrared radiation can potentially induce reactive oxygen

species (ROS) in cutaneous tissue (3-5). ROS are considered to be a major

factor in skin aging, cancer, and other conditions that effect the health of skin.

ROS react with proteins, DNA, and unsaturated fatty acids leading to oxidative

damage and immunosuppression.