ABSTRACT
The deep-sea houses perhaps the most voluminous extreme environments on earth and represents a unique source of microorganisms. Research on piezobiology and their product or enzymes has a great potential of biotechnological applications and research significance (Aguilar, 1996, Pennisi, 1997, Cowan, 1998, Demirjian et al. 2001, Kato et al. 2006). The biotechnological potentials of piezophilic bacteria and piezophilic enzymes have been reviewed by Abe and Horikoshi (2001), Yano and Poulos (2003), Deming (1998), and Gomes and Steiner (2004). Recently, the National Research Council (2002) called for increasing more fundamental understanding of the biosynthetic capabilities of marine organisms for new drugs and agrichemical compounds, developing new paradigms for detecting marine natural products and biomaterials as potential pharmaceuticals, biopolymers, and biocatalysts, and developing new tools to solve environmental problems such as biofouling, pollution, ecosystem degradation, and hazards to human health.
