ABSTRACT

Introduction 185

Screening Tests for Depigmentation Agents 190

Clinical Evaluation 194

The Case of Kojic Acid 200

References 204

INTRODUCTION

There are a variety of facial pigmentary disorders (Table 1). Among such dis-

eases, malignant tumors should be diagnosed and treated properly because

some of them are quick to develop, destructive, or fatal. Hyperpigmentation of

the face of middle-aged women is most common; however, it is benign, and, if

diagnosed and treated properly, it can be cured or greatly improved.