ABSTRACT

Regulatory Environment 545

References 546

REGULATORY ENVIRONMENT

All-trans retinal or retinaldehyde (RAL) belongs to the group of natural retinoids

issued from vitamin A metabolism. Next to retinol, RAL is the key metabolite as

the immediate precursor of retinoic acid (RA) and can be physiologically stored

in the keratinocytes of the skin. With a similar activity (1) and a better tolerability

than RA, RAL is used as cosmetic mainly in skin aging (2).