ABSTRACT
What is specific in ecotoxicological assays? First, dose-response analysis is focusing on potency measures, particularly the no-observed adverse effect level (NOAEL) or the benchmark dose (see Section 7.2). Second, a feasible proof of safety approach is proposed by an authority body, the US EPA [92], denoted as test on significant toxicity (TST). Third, a rather detailed guideline on statistical methods exists [282].
