ABSTRACT

When it comes to building biosensing devices, however, a signal transducer is required in order to take the reaction of the bioreceptor and convert it to a measurable signal. ere are a number of possible signal transduction methods available, generally falling under the categories of optical, electrochemical, or mass-related transduction. Of these categories, optical transduction is by far the most widely utilized, given the variety of spectrochemical properties available to be recorded for any given material. Optical transducers reported in the literature include absorption, reÁection, Áuorescence, Raman, and surface-enhanced Raman scattering. It is in the area of optical signal transduction that the unique optical properties of silicon play a crucial role in the development of new and innovative biosensing devices.