ABSTRACT

Advances in our understanding of the embryogenesis and surgical care of Hirschsprung disease have advanced considerably over the past decade. Despite our increased knowledge of the disease, significant complications continue to be associated with this process. One must maintain a high degree of suspicion for the disease. Suction rectal biopsy and anal manometry studies have allowed for easier and less invasive methods of establishing the diagnosis; however, obtaining details of the infant’s history is the most important first step. Failure to pass meconium within the first 48 hours of life, complaints of constipation and, finally, symptoms of enterocolitis should always be followed by a complete clinical examination for Hirschsprung disease.