ABSTRACT
Ang-2 angiopoietin-2 CD62E E-selectin HMVEC human microvascular endothelial cell HUVEC human umbilical vein endothelial cell ICAM-1 intercellular adhesion molecule 1 IL-1b interleukin-1 beta mRNA messenger ribonucleic acid OPG osteoprotegerin PMN primary polymorphonuclear neutrophil RANKL receptor activator of NF-кB ligand RANK receptor activator of NF-кB siRNA small interfering RNA TNF-α tumour necrosis factor alpha TRAIL tumour necrosis factor-related apoptosis-inducing ligand VCAM-1 vascular cell adhesion molecule 1 VSMC vascular smooth muscle cells
1. In human subjects, high circulating levels of OPG have been associated with a number of diseases where infl ammation is integral in the pathology.
