ABSTRACT
Chemotherapeutic agents of various origins that inhibit the proliferation of cells are called cytostatics. Depending on their point of attack, they may either selectively block individual phases of the cell cycle or disturb cell metabolism in a nonspecific manner. All cytostatics are toxic to healthy body cells, especially to rapidly proliferating tissues (e.g., bone marrow, the epithelium of the small intestine, hair matrix, and testicular tubules). Consequently, the physician must be well aware of the actions and side effects of the individual preparations and dosages must be established case by case and adjusted according to circumstances.
