ABSTRACT
In this chapter the topic is the techniques for preparing pharmaceutical samples for analysis. Sample preparation of pharmaceutical products as well as biological samples is discussed. The scope of this chapter includes only sample preparation for chromatographic analysis in which the chromatographic system, not the sample preparation, achieves the ultimate isolation of the analyte. Isolation and purification of relatively pure substances for spectral analysis, e.g., infrared spectroscopy, nuclear magnetic resonance, and mass spectrometry, will be discussed elsewhere. This chapter is organized into three groups of discussions.
