ABSTRACT

Erythema nodosum (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) Exanthems (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) (1989): McTavish D+, Drugs 38, 19 (1989): Sadick NS+, J Am Acad Dermatol 21, 132 (1989): Stern R+, Arch Intern Med 149, 829 (1983): Lewis JG, Drugs 25, 196 (3.2%) (1982): Anon, Lakartidningen (Swedish) 79, 3822 (1980): Midtbo K+, Curr Ther Res 27, 830 Exfoliative dermatitis (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) (1989): Stern R+, Arch Intern Med 149, 829 Flushing (1-7%) (1992): Shelley WB+, Advanced Dermatologic Diagnosis WB Saunders, 583 (passim) (1989): Mc Tavish D+, Drugs 38, 19 (1-5.4%) (1983): Lewis JG, Drugs 25, 196 (4-7%) (1980): Raftos J, Med J Aust 2, 78 Hyperkeratosis (palms) (<1%) (1989): Sadick NS+, J Am Acad Dermatol 21, 132 (1983): Major P, Tidsskr Nor Laegeforen (Norwegian), 103, 2061 Lichenoid eruption Lupus erythematosus (1998): Callen JP, Academy ’98 Meeting (4 patients) (1997): Crowson AN+, Hum Pathol 28, 67 (subacute cutaneous) Peripheral edema (1-10%) (2002): No author, Medscape Primary Care 4 Photosensitivity (1994): Berger TG+, Arch Dermatol 130, 609 (in HIV-infected) (1989): McTavish D+, Drugs 38, 19 (1983): Lewis JG, Drugs 25, 196 (1979): Anon, Med J Aust 2, 204 Prurigo (sic) (1983): Lewis JG, Drugs 25, 196 Pruritus (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) (1989): McTavish D+, Drugs 38, 19 (1989): Stern R+, Arch Intern Med 149, 829 (1988): Burgunder JM+, Hepatogastroenterology 35, 169 (1983): Lewis JG, Drugs 25, 196 (1982): Fischer Hansen J+, Clin Exp Pharmacol Physiol 6, 31 Purpura (<1%) (1982): Lakartidningen (Swedish) 79, 3822 Rash (sic) (1.2%) (1989): Stern R+, Arch Intern Med 149, 829

(1987): Johnson BF+, Clin Pharmacol Ther 42, 66 Side effects (sic) (1993): Kitamura K+, J Dermatol 20, 279 (psoriasiform) (1989): McTavish D+, Drugs 38, 19.(0.6%) Stevens-Johnson syndrome (<1%) (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) (1992): Gonski PN, Med J Aust 156, 672 (1989): Lin AYF+, Drug Intell Clin Pharm 23, 987 (1989): Stern R+, Arch Intern Med 149, 829 Urticaria (<1%) (1998): Knowles S+, J Am Acad Dermatol 38, 201 (passim) (1989): McTavish D+, Drugs 38, 19 (1989): Sadick NS+, J Am Acad Dermatol 21, 132 (1989): Stern R+, Arch Intern Med 149, 829 (1983): Lewis JG, Drugs 25, 196 Vasculitis (<1%) (1989): Sadick NS+, J Am Acad Dermatol 21, 132 (1983): Lewis JG, Drugs 25, 196

Hair Hair-alopecia (<1%)

(1994): Litt JZ, Beachwood, OH (personal case) (observation) (1991): Shelley WB+, Cutis 48, 364 (observation) (1989): Sadick NS+, J Am Acad Dermatol 21, 132 (1989): Stern R+, Arch Intern Med 149, 829 (1981): Rosing DR+, Am J Cardiol 48, 545 (1980): Rosing DR+, Chest 78(Suppl), 239 Hair-hypertrichosis (1991): Sever PS, Lancet 338, 1215 Hair-pigmentation (1991): Read GM, Lancet 338, 1520

Nails Nails-dystrophy

(1989): Stern R+, Arch Intern Med 149, 829

Other Erythromelalgia

(1992): Drenth JP+, Br J Dermatol 127, 292 Galactorrhea (<1%) Gingival hyperplasia (19%) (1995): Moghadam BKH+, Cutis 56, 46 (passim) (1993): Steele RM+, Arch Intern Med 120, 663 (1989): Pernu HE+, J Oral Pathol Med 18, 422 (1987): Giustiniani S+, Int J Cardiol 15, 247 Gynecomastia (<1%)

(2000): Hugues FC+, Ann Med Interne (Paris) (French) 151, 10 (passim) (1994): Deniel-Rosanas J, Med Clin (Barc) (Spanish) 102, 399 (1994): BMJ 308, 503 (1988): Tanner LA+, Arch Intern Med 148, 379 Headache Paresthesias (<1%) Parkinsonism (2003): Prescrire Int 12(64), 62 Rhabdomyolysis (2000): Gokel Y+, Am J Emerg Med 18, 738 (with trandolapril) Serum sickness (1989): Pascual-Velasco F, Med Clin (Barc) (Spanish) 92, 719 Xerostomia (<1%)

Trade name: Visudyne (Novartis) Indications: Wet form of age-related macular degeneration Category: Macular degeneration adjunct; Photosensitizer Half-life: 5-6 hours

Reactions

Skin Cheilitis

(1998): Mitchell D, Thomasville, GA (from Internet) (observation) Chills Diaphoresis Eczema (sic) (1-10%) Erythema Flu-like syndrome (1-10%) Ocular pruritus Pallor Photosensitivity (<3%) (2002): Houle JM+, Retina 22(6), 691 (2000): Scott LJ+, Drugs Aging 16, 139 Pigmentation Pruritus Purpura Rash (sic) Shivering

Ulcerations Urticaria (1998): Mitchell D, Thomasville, GA (generalized) (from Internet) (observation) Vesicular eruptions (1998): Mitchell D, Thomasville, GA (from Internet) (observation)

Other Arthralgia (1-10%)

Burning mouth syndrome (1-10%) (1998): Mitchell D, Thomasville, GA (from Internet) (observation) Chest pain (2003): Prescrire Int 12(63), 17 (2002): Cahill MT+, Am J Ophthalmol 134(2), 281 Hyperesthesia (1-10%) Injection-site pain (2000): Scott LJ+, Drugs Aging 16, 139 Injection-site reactions (sic) Pain (chest and neck) (2002): Cahill MT+, Am J Ophthalmol 134(2), 281 Paresthesias

Synonyms: adenine arabinoside; ara-A Trade name: Vira-A Ophthalmic (Parke-Davis) Other common trade names: Adena a Ungena; Arasena Indications: Herpetic keratoconjunctivitis Category: Ophthalmic antiviral Half-life: 3.3 hours Clinically important, potentially hazardous interactions with: insulin

Reactions

Skin Ocular burning

Ocular erythema Ocular pruritus Pruritus Rash (sic)