ABSTRACT
To ensure the suitability of solid lipid nanoparticle dispersions for the intended type of application, and to enable a focused development of dispersions with specific properties, the characteristics of the dispersions have to be known in detail. A major point of interest is the question of sufficient colloidal stability of these thermodynamically labile systems. However, a detailed characterization of these systems is also very important when it is considered that the material properties of solid lipids, particularly the melting, crystallization, and polymorphic behavior of these lipids, may change dramatically when the substances are dispersed into particles in the lower nanometer size range.
