ABSTRACT

All antithrombotic treatments affect the hemostatic system and are therefore associated with a risk of bleeding which is the most important critical point for the safety of these treatments. The expected rate of bleeding complications, especially major ones, is the crucial factor determining the evaluation of risks/ benefits of antithrombotic agents. Accurate information on the risk of hemorrhage of the various antithrombotic treatments in the different clinical conditions is, however, not easy to achieve.