ABSTRACT

This text examines the relationship between DNA damage and repair, cellular senescence, genomic instability, and aging. The authors provide in-depth discussions of various types of DNA damage, the DNA repair network, and cellular responses to genetic damage to assess their impact on the modulation of aging processes and age-related diseases, includ

chapter 1|8 pages

Introduction

chapter 3|22 pages

Cellular Senescence

chapter 6|18 pages

Role of Ku at the Telomere

chapter 9|20 pages

Werner Syndrome

chapter 13|48 pages

Ataxia-Telangiectasia

chapter 15|30 pages

Dyskeratosis Congenita

chapter 17|32 pages

Xeroderma Pigmentosum