ABSTRACT
I. Introduction 286
II. Subjective Complaints and Clinical Findings 287 III. Experimental Studies with Various Fish Products 289
IV. Comparison of Subjective and Experimental Results 292 V. Cause of Skin Symptoms 294
A. Lipid and Protein Fraction 295
B. High and Low Molecular Weight Compounds 295
C. Protein Concentration and Peptide Pattern 295
D. Degradation Products 295
E. Bacteria and Algae 296
VI. The Effects of Cold Exposure on Itch and Erythema 299
VII. Skin Physiological Measurements 301
VIII. The Effect of Cold Exposure on Skin Barrier Recovery 305
IX. Comments and Conclusions 307
A. Skin Symptoms 307
B. Cold and Location of the Symptoms 310
C. Skin Physiological Measurements and Barrier Function 312
References 314
I. INTRODUCTION
In Denmark, skin diseases rank as the third most common reported occupational disease, and 94% of the cases are contact dermatitis.1 However, among young people (′ 25 years), occupational skin diseases rank first. The single most commonly recognized occupational disorder is contact dermatitis1 Therefore, occupational contact dermatitis causes many socioeconomic problems.
