ABSTRACT

Once we overcame the hypothesis that renal cell carcinoma (RCC) was the malignant transformation of intrarenal adrenal remnants, it was considered that all renal parenchymal neoplasias originated in the proximal tubules1. For this reason, only grading, staging and some morphological characteristics such as spindle cell phenotype are generally used to describe biological differences between patients. However, in the literature, various morphological forms are described, involving growth (papillary renal cell carcinoma) or cytological features (chromophobe cell carcinoma, chromophil cell carcinoma, granular cell carcinoma)2. Also described is the concept of oncocytoma as a benign biological neoplasia3.