ABSTRACT
Abstract. This chapter describes the model-based analysis of oligonucleotide arrays, including expression index computation, outlier detection, and standard error applications, as well as issues in the analysis of cDNA array data such as normalization, handling of replicate arrays and spots, and hierarchical modeling of the data in detecting differentially expressed genes. Software implementing these analysis methods can be found at https://biosun1.harvard.edu/complab/.
