ABSTRACT
Large defects of the thoracic and abdominal wall that result from trauma, tumor ablation, infection, or radiation may significantly impair function of those important structures, may expose vital organs with life-threatening consequences, and may cause gross deformity. Reconstruction of thoracic and abdominal wall defects should aim to restore structure and provide stable soft tissue coverage. Restoring structure will allow for normal respiration, protect viscera and vasculature, and correct or prevent hernias of the abdominal wall. Soft tissue reconstruction should provide stable coverage as well as a cosmetically acceptable result. Judicious use of skin, fascial, and bone grafts, soft tissue flaps, and alloplastic materials for skeletal and fascial support should be used for component restoration of complex defects.
