ABSTRACT

Multiple sclerosis (MS) is a disorder with central nervous system (CNS) lesions disseminated in time and space. In patients with suspected MS, therefore, paraclinical tests serve the purposes of discovering clinically silent lesions and of excluding other disorders. In patients with an established diagnosis of MS, tests are conducted to objectively monitor the actual course and to predict the future course. Moreover, they may yield insight into the natural history and the mechanisms of pathology of the disease.