ABSTRACT

The orthodox view that psychotic disorders can be divided into schizophrenia and bipolar disease stems from extensive clinical observations by Emil Kraepelin in the early years of the twentieth century.1 Current psychiatric nosology, whether American or European, classifies schizophrenia and bipolar disorder as two distinct diagnostic categories, with presumed independent aetiologies, and any clinical overlap at the patient or family levels tends to be attributed to diagnostic misclassification.