ABSTRACT

Genital ulceration is defined as lesions characterized by the loss of epithelium in the skin or mucosa of the genital area. A regional lymphadenopathy often accompanies the ulceration. The combination of ulceration and lymphadenopathy constitutes the genital ulcer adenopathy syndrome. The importance of genital ulcer disease has increased considerably since it became evident that these lesions may increase the risk of HIV transmission.