ABSTRACT
The stages of initiation and promotion were discussed in Chapter 7 as the beginning processes leading to the ultimate development of cancer. However, it should be clear to the reader that many of the behavioristic characteristics of malignancy (Chapter 2) are not expressed in the stages of initiation and promotion. Thus, the cellular populations of these stages are rightfully said to represent preneoplasia. It is in the final stage of neoplastic development, the stage of progression, that neoplasia is expressed as a true clinical disease condition.
